Standard Reference Materials: A Fluorescence Standard Reference Material: Quinine Sulfate Dihydrate

Standard Reference Materials :: A fluorescence standard reference material /
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Diverse applications of luminescence from varied sources exist. This is when a semiconductor light source emits light if a current flow through it []. Also phosphorescence finds innumerable applications [,]. Phosphor thermometry is another application consisting in measuring surface temperatures by an optical method that uses phosphor as a light emitter [].

The thermoluminescence method is when a crystal material previously exposed to heating, is dated on the basis of light emitted by the body under survey on the time []. The tool employed is a thermoluminescent dosimeter [,]. Gingerol [ 5 hydroxy-l- 4-hydroxymethoxyphenyl decanone] is a natural product characterized as the active principie of ginger Zingiber officinale and it gives it its spicy flavor and properties.

Gingerol is related structurally to capsaicin and piperine, both constituents of black pepper and chili peppers and responsible of their spiciness [].

Fluorescence standard reference material quinine sulfate dihydrate free

A Fluorescence Standard Reference Material: Quinine Sulfate Dihydrate. R. A. Velapoldi and K. D. Mielenz. Author Information. Standard Reference Materials: A Fluorescence Standard Reference Material: Quinine Sulfate Dihydrate. 8 R. A. Velapoldi and K. D. Mielenz. National.

Among the biological activities described for gingerol, one of them induces hypothermia in rats []. In the animal model, gingerol is apparently effective for the rheumatoid arthritis []. Quinine sulfate is a presentation of quinine which together with cinchonamine constitutes the very important group of the cinchona alkaloids []. The alkaloids of the quinine subgroup contain a quinoline ring system generated from the same precursor of cinchonamine subgroup []. The cinchona alkaloids are present in three botanical families: Rubiaceae, Apocynaceae and Oleaceae [], where twenty-four cinchona alkaloids of cinchona species have been described and regrouped in four subclasses, quinine, quinidine, cinchonidine and cinchonine [].

Cinchona alkaloids have been used for the treatment of malaria since centuries ago [].

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Its most important antimalarial principie is quinine active against Plasmodium falciparum []. In spite of its long liveness, quinine is still an antimalarial alternative when resistance to chloroquine manifests and when artesunate is not available []. Quinine sulfate is a way for administering quinine. Quinine sulfate is offered in the market in the form of tablets for instance.

Its therapeutic indications include the treatment of malaria or malignant tertian fever provoked by Plasmodium falciparum, and the treatment and prophylactic action for leg cramps during sleep in aged people []. Fluorescein is a synthetic phenolic and it has dye properties. It is used as a fluorescent tracer in many applications. As a fluophore is used in microscopy and applied in forensics and serology. In medicine it's of extensive use in ophthalmology and optometry []. The luminescent properties of 6-gingerol and derivatives have been employed in many analytical assays due to their luminescent properties as shown extensively in the literature [].

Quinine sulfate fluorescence has been widely studied and applied in analyses of diverse nature []. Fluorescence is a kind of photoluminescence as a result of emission of light of a different wave-lenght to the UV irradiation applied to the sample. Fluorescein, quinine sulfate and gingerol possess fluorescence properties. Fluorescein is a reddish crystal soluble in ethanol but not in water, it produces an intense greenish fluorescence at pH 8 due to nm irradiation, it has been synthesized in lab by condensation of ftalic anhydride and resorcinol.

Quinine is a quinoline-type alkaloid which is extractable from its natural source, the stem-bark of Cinchona calisaya, by means of organic solvents and sulfuric acid. The extract is a brownish powder whose purification under alumina percolation afforded cinchona alkaloids. The quinine sulfate purified by crystallization is a white powder which once dissolved in ethanol and irradiated under UV light emits fluorescent light. The most intense fluorescence was that of fluorescein. Lum, Q.

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